Why the study?
Does the modification of treatment strategies over a 14-year period reduce cardiac events in post-myocardial infarction patients?
Population
6,602 post-myocardial infarction patients enrolled between 1986 and 1999.
Comparison
Implementation of new therapeutic modalities… vs Historical treatment strategies from earlier in…
Design
Cohort
Follow-up
average 12.6 +/- 16.3 months
Authors
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Declining post-MI event rates coincided with evolving care; leaves open whether treatment changes drove the trend in this observational cohort.
Does the modification of treatment strategies over a 14-year period reduce cardiac events in post-myocardial infarction patients?
The evolution of post-MI treatment strategies over 14 years, including increased use of revascularization and evidence-based medical therapy, was associated with a significant 50% reduction in the incidence of cardiac events.
Ishikawa et al. (2002) studied this question.
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