Why the study?
Does alteration of blood pressure and metabolic rate affect the amplitude and frequency of oxygen availability cycles?
Does alteration of blood pressure and metabolic rate affect the amplitude and frequency of oxygen availability cycles?
Oxygen availability cycles are dependent on mean arterial blood pressure and metabolic rate, suggesting a feedback mechanism between CO2 generation and precapillary arteriole pH sensitivity.
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Animal data tie oxygen cycles to BP and metabolism; hypothesis-generating for human cerebrovascular autoregulation, needs confirmation.
Halsey et al. (1974) studied this question.
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