What question did this study set out to answer?

To validate an automated method for generating three-dimensional finite element models of bone directly from computed tomography scan data.

Validation of an automated method of three-dimensional finite element modelling of bone

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Biomechanical study demonstrates accurate strain prediction in a cadaveric femur, indicating the reliability of automated finite element bone models.

To validate an automated method for generating three-dimensional finite element models of bone directly from computed tomography scan data.
Constructed an automated finite element model from CT scan data of a fresh-frozen cadaveric femur.
Attached physical strain gauges across 11 femoral locations and applied mechanical loads to the femoral head.
Assessed the association between model-predicted strains and experimentally measured surface strains using linear regression analysis.
Strains calculated by the automated finite element model demonstrated a statistically significant correlation with measured surface strains (P < 0.001).
Surface strain validation supported the computational accuracy of strains and stresses predicted deeper within the bone tissue.

Keyak et al. (1993) studied this question.

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Biomechanical study demonstrates accurate strain prediction in a cadaveric femur, indicating the reliability of automated finite element bone models.