Population
Dogs anaesthetized with chloralose
Comparison
Increases in left ventricular systolic pressure… vs Large change in carotid sinus pressure or aortic…
Design
Preclinical
Authors
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Supports ventricular depressor reflexes in animal models; leaves open translation to human physiology.
Increases in left ventricular pressure result in significant peripheral vasodilation, particularly when pressure is moderately elevated.
Challenger et al. (1987) studied this question.
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