Key result
Ivabradine monotherapy achieved adequate rate control of focal junctional tachycardia in a dog with severe myxomatous mitral valve disease and congestive heart failure.
Why the study?
Does ivabradine improve rate control in a dog with focal junctional tachycardia?
Case Report (n=1)
Does ivabradine improve rate control in a dog with focal junctional tachycardia?
Ivabradine may be a useful monotherapy for rate control of focal junctional tachycardia in dogs.
Hypothesis-generating case of junctional tachycardia in canine MMVD with biventricular failure; prospective studies needed before guiding therapy.
A 10‐year‐old labrador retriever was referred as an emergency due to ascites and lethargy. Physical examination revealed a regular tachycardia at 160 beats per minute with a Grade 3/6, left apical systolic heart murmur. The dog was diagnosed with severe myxomatous mitral valve disease with biventricular congestive heart failure (mild pulmonary oedema and severe ascites) and focal junctional tachycardia. Congestive heart failure was managed with pimobendan, furosemide and benazepril/spironolactone. Ivabradine, a funny channel blocker, was used for rate control of the focal junctional tachycardia, and the dog achieved adequate rate control with monotherapy. The dog was euthanased 10 months after the initial presentation due to refractory congestive heart failure. This case report suggests that ivabradine might be useful for rate control in focal junctional tachycardia, but further studies are required to confirm this observation.
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Escalda et al. (2025) conducted a case report in Focal junctional tachycardia and severe myxomatous mitral valve disease with biventricular congestive heart failure (n=1). Ivabradine was evaluated on Rate control of focal junctional tachycardia. Ivabradine monotherapy achieved adequate rate control of focal junctional tachycardia in a dog with severe myxomatous mitral valve disease and congestive heart failure.
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