Why the study?
Does the type 1 EWS-FLI1 fusion transcript structure improve overall survival in patients with Ewing's sarcoma compared to less common fusion types?
Population
99 patients with Ewing's sarcoma treated with curative intent, in which EWS-FLI1 fusion transcripts were…
Comparison
Type 1 EWS-FLI1 fusion transcript vs Less common EWS-FLI1 fusion types
Design
Cohort
Follow-up
median 26 months (range, 1 to 140 months)
Authors
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Type 1 EWS-FLI1 fusion may refine prognostication in Ewing sarcoma; leaves open whether it should guide therapy.
Does the type 1 EWS-FLI1 fusion transcript structure improve overall survival in patients with Ewing's sarcoma compared to less common fusion types?
The type 1 EWS-FLI1 fusion transcript is an independent positive prognostic factor for overall survival in patients with Ewing's sarcoma.
Kawai et al. (1998) studied this question.
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