Key result
18F-FDG PET/CT scan successfully identified systemic metastases in a 27-year-old woman with primary Ewing sarcoma of the kidney following radical nephrectomy and adjuvant chemotherapy.
Why the study?
Primary Ewing sarcoma or primitive neuroectodermal tumour is rare in adults, and primary renal involvement is extremely rare.
Case Report (n=1)
No
18F-FDG PET/CT scan is useful for restaging and detecting metastases in primary Ewing sarcoma of the kidney.
May support 18F-FDG PET/CT for metastasis detection in renal Ewing sarcoma; hypothesis-generating and leaves open need for validation.
Primary Ewing sarcoma (ES) or primitive neuroectodermal tumour (PNET) is a rare tumour in adults and primary renal involvement is extremely rare. Patients with renal ES or PNET respond to and would benefit from conventional ES treatment according to ES study protocols. Here, we report a case of a young woman, presenting with right flank pain and haematuria. After ultrasound and CT evaluation, a right middle pole renal mass was detected. The patient underwent radical right nephrectomy, and a grade 4 ES with peritoneal involvement was documented. Subsequently, the patient underwent adjuvant chemotherapy for 5 months. Follow-up 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT scan demonstrated bilateral cervical, hilar, mediastinal and retroperitoneal FDG-avid adenopathies associated with mild right-sided pleural effusion with no metabolic activity, signifying the role of PET/CT scan in tumour restaging.
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Doroudinia et al. (2019) conducted a case report in Primary Ewing sarcoma of the kidney (n=1). Radical nephrectomy and adjuvant chemotherapy was evaluated on Tumour restaging and detection of metastases. 18F-FDG PET/CT scan successfully identified systemic metastases in a 27-year-old woman with primary Ewing sarcoma of the kidney following radical nephrectomy and adjuvant chemotherapy.
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