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January 1, 2015journal of Anesthesiology and Clinical ScienceOpen Access

Prophylactic use of IV atropine for prevention of spinal anesthesia induced hypotension and bradycardia in elderly: a randomized controlled trial

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Key result

Spinal anesthesia results in hypotension in 33% and bradycardia in 13% of patients due to sympathetic blockade-induced systemic vasodilation.

Why the study?

Does prophylactic intravenous atropine prevent spinal anesthesia induced hypotension and bradycardia in elderly patients?

Population

Elderly patients undergoing spinal anesthesia

Design

RCT

Authors

SSShailendra SigdelManhattan Institute for Policy Research

Discussion

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Implication

Requires heightened vigilance for hemodynamic instability during spinal anesthesia in elderly patients; confirms sympathetic blockade mechanism, supporting targeted prophylaxis trials.

Structured PICO

Does prophylactic intravenous atropine prevent spinal anesthesia induced hypotension and bradycardia in elderly patients?

P
Population
Elderly patients undergoing spinal anesthesia
I
Intervention
Prophylactic intravenous atropine
O
Outcome
Prevention of spinal anesthesia induced hypotension and bradycardiasafety

Cite This Study

Shailendra Sigdel (2015) studied this question. Spinal anesthesia results in hypotension in 33% and bradycardia in 13% of patients due to sympathetic blockade-induced systemic vasodilation.

synapsesocial.com/papers/6a915288cad91ca1da4f08e7https://doi.org/10.7243/2049-9752-4-5
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Incidence and Risk Factors for Side Effects of Spinal Anesthesia1992 · 637 citations
  2. 2Effect of Pre-medication with Atropine on the Blood Pressure of Parturient Undergoing Caesarian Section under Spinal Anaesthesia2004 · 10 citations
  3. 3Prolonged PR Interval Is a Risk Factor for Bradycardia During Spinal Anesthesia1995 · 16 citations
  4. 4Unexpected Cardiac Arrest during Spinal Anesthesia1988 · 442 citations
  5. 5The Use of Intravenous Atropine After a Saline Infusion in the Prevention of Spinal Anesthesia-Induced Hypotension in Elderly Patients2000 · 45 citations