Key result
Transcatheter closure of perimembranous ventricular septal defect with indirect Gerbode defect using double-disc devices was successful in all 14 patients, completely eliminating the VSD.
Why the study?
Perimembranous VSD with indirect Gerbode defect rarely closes spontaneously and was typically treated surgically, with transcatheter closure reported by only a few authors.
Does transcatheter device closure improve shunt elimination in children with pmVSD associated with indirect Gerbode defect?
Observational (n=14)
No
Does transcatheter device closure improve shunt elimination in children with pmVSD associated with indirect Gerbode defect?
Transcatheter closure using double-disc devices is an efficacious strategy for occluding pmVSD associated with indirect Gerbode defect in children.
Supports feasibility of transcatheter closure for indirect Gerbode defect in children; hypothesis-generating pending controlled trials.
Perimembranous ventricular septal defect (pmVSD) is a common congenital heart disease that is sometimes associated with indirect left ventricle (LV) to right atrium (RA) shunt (indirect Gerbode defect). This defect has a rare chance of spontaneous closure and therefore was usually closed surgically in the past, but more recently transcatheter closure has been reported by a few authors. In our study, we have described a series of 14 children (age ranging from 1.2 to 12 years and weight ranging from 7.2 to 25.5 kg) with the above-mentioned defect which were closed by various interventional devices. The procedures were successful in complete elimination of pmVSD and immediate reduction of indirect LV-RA shunts with negligible residual tricuspid regurgitation on follow-up. In our midterm experience, the judicious use of double-disc devices is efficacious for occluding pmVSD associated with indirect Gerbode defect.
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Parvez et al. (2021) conducted an observational in Perimembranous ventricular septal defect with indirect Gerbode defect (n=14). Transcatheter device closure (double-disc devices) was evaluated on Successful device placement and elimination of pmVSD. Transcatheter closure of perimembranous ventricular septal defect with indirect Gerbode defect using double-disc devices was successful in all 14 patients, completely eliminating the VSD.
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