Why the study?
Does coronary sinus pacing alter aortic and coronary sinus catecholamine levels in patients with cardiac ischemia compared to controls?
Population
16 subjects (8 patients with cardiac ischemia and 8 control subjects)
Comparison
Coronary sinus pacing to peak rates vs Control subjects without ischemia undergoing…
Design
Case-control
Authors
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Blunted myocardial norepinephrine release during pacing in ischemia may reflect autonomic impairment; hypothesis-generating and should not yet change practice.
Does coronary sinus pacing alter aortic and coronary sinus catecholamine levels in patients with cardiac ischemia compared to controls?
Pacing-induced angina does not augment peripheral sympathetic activity but is associated with a blunted increase in cardiac sympathetic tone compared to controls.
Schwartz et al. (1979) studied this question.
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