Why the study?
Does the occurrence of angina during exercise alter the cardiac sympathetic response in patients with coronary artery disease compared to those without angina and normal controls?
Population
40 subjects, including 31 patients with coronary artery disease and 9 normal control subjects. The CAD…
Comparison
Supine bicycle exercise vs Normal control subjects and CAD patients without…
Design
Cross-sectional
Authors
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Angina during exercise may mark heightened cardiac sympathetic activation in CAD; leaves open causal role and therapeutic targeting in prospective studies.
Does the occurrence of angina during exercise alter the cardiac sympathetic response in patients with coronary artery disease compared to those without angina and normal controls?
The occurrence of angina during exercise selectively enhances the cardiac sympathetic response, whereas CAD patients without angina have sympathetic responses similar to normal controls.
McCance et al. (1989) studied this question.
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