Population
Garter snake twitch-muscle endplates
Comparison
Temperature variation and ion replacement vs Normal saline (Na+)
Design
Preclinical
Authors
Loading...
Animal AChR data warrant no clinical ion channel adjustments; leaves open human translation and Eyring model validation.
The study demonstrates that acetylcholine receptor channel conductance increases with temperature and varies by ion type, which can be modeled by an Eyring-type model with a single energy barrier.
Hoffmann et al. (1983) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: