Cortisone and A.C.T.H. in Treatment of Non-rheumatic Conditions

of the drug, which had been given at a dosage of 25 mg. daily, and splenectomy was undertaken during a second course of A.C.T.H. Relapse again occurred when the drug was discontinued. A third course of A.C.T.H., later changed to cortisone, was continued in gradually diminishing dosage for a further period of 14 weeks, and no ill effects have attended its final withdrawal, 28 weeks after the onset. The direct Race- Coombs test, positive at the outset, is now only weakly so.