Key result
When medical eligibility criteria are strictly followed, the absolute risk of venous thromboembolism with combined hormonal contraceptives is extremely low (1-3 cases per 10,000 women) and is outweighed by the benefits.
Why the study?
Do oral and non-oral combined hormonal contraceptives increase the risk of venous thromboembolism in women of reproductive age?
Population
Women of reproductive age
Comparison
Oral and non-oral combined hormonal contraceptives vs No hormonal contraception or other…
Design
Review
Authors
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Supports low VTE risk with combined hormonal contraceptives under eligibility criteria; leaves open need for prospective validation in diverse populations.
Do oral and non-oral combined hormonal contraceptives increase the risk of venous thromboembolism in women of reproductive age?
When WHO medical eligibility criteria are strictly followed, the use of combined hormonal contraceptives carries a clinically insignificant absolute risk of venous thromboembolism that is outweighed by their benefits.
Татарчук et al. (2014) conducted a review in Venous thromboembolism risk. Combined hormonal contraceptives (oral and non-oral) vs. Non-use of hormonal contraception was evaluated on Venous thromboembolism (VTE). When medical eligibility criteria are strictly followed, the absolute risk of venous thromboembolism with combined hormonal contraceptives is extremely low (1-3 cases per 10,000 women) and is outweighed by the benefits.
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