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Fine-needle biopsy has been performed on a healthy subject without any signs of liver disease, especially none of cholestasis. During aspiration, bile appeared in the syringe, and laparotomy was necessary 24 hours later. About 1.5 l bile was found in the abdominal cavity; no lesions of the biliary system could be seen. Treated with drainage, the further course was uncomplicated.
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Tom Schulz (1976) studied this question.
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