Key result
Catheter-directed thrombolysis with 50 mg of r-TPA successfully reduced pulmonary artery pressure to 50 mmHg and relieved dyspnea in a patient with sub-massive pulmonary embolism after failed systemic thrombolysis.
Case Report (n=1)
No
This case demonstrates the feasibility and safety of sequential systemic and catheter-directed thrombolysis for sub-massive pulmonary embolism.
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Supports sequential thrombolysis after systemic failure in sub-massive PE; hypothesis-generating and should not change practice without randomized data.
Castillo et al. (2014) conducted a case report in Sub-massive pulmonary embolism (n=1). Catheter-directed thrombolysis with r-TPA was evaluated on Reduction in pulmonary artery pressure and relief of symptoms. Catheter-directed thrombolysis with 50 mg of r-TPA successfully reduced pulmonary artery pressure to 50 mmHg and relieved dyspnea in a patient with sub-massive pulmonary embolism after failed systemic thrombolysis.
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