Why the study?
Acceptable blood pressure control in hemodialysis patients is challenging due to multifactorial etiology, prompting a study to identify the best drug or drug combination to control blood pressure.
Does the combination of amlodipine and metoprolol improve blood pressure control across dialysis phases in patients with end-stage renal disease on hemodialysis?
Observational (n=553)
Yes
Does the combination of amlodipine and metoprolol improve blood pressure control across dialysis phases in patients with end-stage renal disease on hemodialysis?
Absolute Event Rate: 122.29% vs 161.72%
p-value: p=<0.0001
In patients with end-stage renal disease on hemodialysis, the combination of amlodipine and metoprolol provided effective blood pressure control across all phases of dialysis with minimal intra-dialytic complications.
Cardiac problems are the foremost reason for morbidity and mortality in patients with end-stage renal disease caused by hemodialysis. Many of these patients suffer from increased blood pressure, and acceptable control of blood pressure is a task in these patients because of multifactorial etiology. The present study aims to find out the best possible drug or combination of drugs that can better control blood pressure and improve the quality of life of these patients. It is a multi-centered retrospective study design it was accessed in the patients who visited the Haemodialysis unit of Nephrology unit of Mahatma Gandhi Memorial Hospital, Warangal and Vishwas Super Speciality Hospital, Hanamkonda. The collected data related to demographic characteristics, comorbidities, clinical pathology parameters, current therapy of antihypertensive drugs and blood pressure control (pre-dialysis and post-dialysis) were noted and analysed. 56.60 % of patients on hemodialysis who are suffering from hypertension with the age group of 41-60 y (46.47 %) majority of the population was illiterates with a count of 210 (37.97 %) and business people were of 196 (35.44 %). A combination of amlodipine with metaprolol most frequently prescribed agents (31.82 %), it was significantly (p<0.0001) reducing the systolic blood pressure and diastolic blood pressure in intra (142.80±14.49; 75.13±7.56), post-dialysis (122.29±10.81; 67.91±7.64) respectively compared with pre-dialysis (161.72±14.78; 81.66±.6.99). The mean intradialytic weight gain was 2.65 kg. In post dialysis treatment, the greatest mean (95 % confidence interval) changes in creatinine (p<0.0353), albumin (p<0.0001), Kt/v (p<0.0001 and mean arterial pressure reduced (p<0.0001) in post-dialysis compared to pre-dialysis respectively. The combination of amlodipine with metaprolol frequently prescribed medication provides adequate blood pressure control in all phases of dialysis with the least intra-dialysis complication. sex video hindi xxx, mallu sex videos, desi aunty fuking in clear telugu voice, xxx sunny leone xxx bf, www xnxx com, Indian hidden camera shower
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Gaddam et al. (2023) conducted an observational in End Stage Renal Disease with Hypertension (n=553). Amlodipine and metoprolol vs. Pre-dialysis baseline was evaluated on Systolic blood pressure (post-dialysis vs pre-dialysis) (p=<0.0001).
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