Key result
AF is linked to higher uNAG, uKIM, and NT-proBNP versus sinus rhythm in acute chest pain.
Why the study?
Acute heart disorders often feature the coexistence of AF and cardiorenal syndrome, prompting evaluation of the cardiorenal biomarkers uNAG and uKIM in real-world acute chest pain patients according to rhythm.
Are urinary biomarkers of renal tubular injury (uNAG, uKIM) and NT-proBNP associated with atrial fibrillation in patients presenting with acute chest pain?
Observational (n=601)
No
Are urinary biomarkers of renal tubular injury (uNAG, uKIM) and NT-proBNP associated with atrial fibrillation in patients presenting with acute chest pain?
In patients presenting with acute chest pain, elevated levels of renal tubular injury biomarkers (uNAG) and NT-proBNP are independent predictors of atrial fibrillation.
AF linked to higher tubular biomarkers in chest pain; leaves open causality and clinical utility in cardiorenal syndrome.
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Lang et al. (2026) conducted an observational in acute chest pain (n=601). Atrial fibrillation vs. Sinus rhythm was evaluated on Urinary concentrations of uNAG, uKIM, and NT-proBNP (p=<0.001). Atrial fibrillation was associated with significantly increased concentrations of uNAG, uKIM, and NT-proBNP compared to sinus rhythm in patients with acute chest pain (p<0.001).
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