Hepatitis A Revisited

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Editorials1 December 1986Hepatitis A RevisitedDAVID J. GOCKE, M.D.DAVID J. GOCKE, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-105-6-960 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe perception seems widespread that hepatitis A virus does not cause chronic disease, rarely causes fulminant hepatitis, is not associated with extrahepatic manifestations, and results in only a benign, self-limited disease generally confined to underdeveloped countries and occasional foodborne or waterborne outbreaks in this country. Certainly, hepatitis A virus does not match the propensity of hepatitis B virus to cause any of these potentially calamitous complications. Even the elusive non-A, non-B hepatitis viruses, for which a specific serologic marker is still lacking, engender more respect because of their association with post-transfusion hepatitis and chronic liver injury. Also, interest generated by...References1. INMAN R, HODGE M, JOHNSTON M, WRIGHT J, and HEATHCOTE J. Arthritis, vasculitis, and cryoglobulinemia associated with relapsing hepatitis A infection. Ann Intern Med. 1986;105:700-3. LinkGoogle Scholar2. ROUTENBERG J, DIENSTAG J, and HARRISON W. Foodborne outbreak of hepatitis A: clinical and laboratory features of acute and protracted illness. Am J Med Sci. 1979;278:123-31. CrossrefMedlineGoogle Scholar3. WEIR W, MELLOR J, SMITH H, and TYRRELL D. Significance of hepatic enzyme levels at discharge in acute viral hepatitis. J Infect. 1981;3:309-15. CrossrefMedlineGoogle Scholar4. MEIER E, RICHTER K, and FRUHMORGEN P. [Transient chronic hepatitis after acute viral hepatitis A.] Dtsch Med Wochenschr. 1982;107:46-50. CrossrefMedlineGoogle Scholar5. JACOBSON I, NATH B, and DIENSTAG J. Relapsing viral hepatitis type A. J Med Virol. 1985;16:163-9. CrossrefMedlineGoogle Scholar6. GORDON S, REDDY K, SCHIFF L, and SCHIFF E. Prolonged intrahepatic cholestasis secondary to acute hepatitis A. Ann Intern Med. 1984;101:635-7. LinkGoogle Scholar7. KAO H, ASHCAVAI M, and REDEKER A. The persistence of hepatitis A IgM antibody after acute clinical hepatitis A. Hepatology. 1984;4:933-6. CrossrefMedlineGoogle Scholar8. STEWART J, FARROW L, and CLIFFORD R. A three-year survey of viral hepatitis in West London. Q J Med. 1978;47:365-84. MedlineGoogle Scholar9. GIMSON A, WHITE Y, EDDLESTON A, and WILLIAMS R. Clinical and prognostic differences in fulminant hepatitis type A, B and non-A non-B. Gut. 1983;24:1194-8. CrossrefMedlineGoogle Scholar10. NOBLE R, KANE M, REEVES S, and ROECKEL I. Posttransfusion hepatitis A in a neonatal intensive care unit. JAMA. 1984;252:2711-5. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: DAVID J. GOCKE, M.D.Affiliations: University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School New Brunswick, New Jersey PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byVacunación universal frente a la hepatitis ANon–North American Travel and Exotic DiseasesIn the Eye of the Beholder:Brote comunitario de hepatitis A en un grupo de etnia gitana: control mediante la vacunación antihepatitis AHepatitis A vaccination policy in Catalonia (Spain)Chronic liver diseaseCholestatic hepatitis, cutaneous vasculitis, and vascular deposits of immunoglobulin M and complement associated with hepatitis A virus infectionProlonged IgM antibodies and histopathological evidence of chronicity in hepatitis APrognosis of Acute Viral Hepatitis Now You Got It, Now You Don’t (Or Do You?) 1 December 1986Volume 105, Issue 6Page: 960-961KeywordsChronic hepatitisHepatitis AHepatitis A virusHepatitis B virusHepatitis virusesLiverPerception ePublished: 1 December 2008 Issue Published: 1 December 1986 PDF downloadLoading ...