Key result
Percutaneous and surgical ASD closure both reduced RV end-diastolic diameter z score from a median of 5.00 to 2.25 SD (P<0.001), but percutaneous closure led to faster LV size normalization.
Why the study?
Does percutaneous ASD closure improve hemodynamics faster than surgical closure in children with ASD?
Population
24 children with atrial septal defect and 51 healthy control children.
Comparison
Percutaneous ASD closure vs Surgical ASD closure
Design
Cohort
Follow-up
1 year
Authors
Loading...
Percutaneous ASD closure may accelerate pediatric LV normalization; observational data leaves open need for randomized outcome trials.
Cohort (n=75)
Does percutaneous ASD closure improve hemodynamics faster than surgical closure in children with ASD?
p-value: p=<0.001
Percutaneous ASD closure in children is associated with faster normalization of left ventricular size and natriuretic peptide levels compared to surgical closure.
Eerola et al. (2006) conducted a cohort in Atrial septal defect (ASD) (n=75). Percutaneous ASD closure vs. Surgical ASD closure was evaluated on RV end-diastolic diameter z score (p=<0.001). Percutaneous and surgical ASD closure both reduced RV end-diastolic diameter z score from a median of 5.00 to 2.25 SD (P<0.001), but percutaneous closure led to faster LV size normalization.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: