Key result
Acute-phase glucose fluctuation was significantly negatively correlated with the myocardial salvage index 7 days after successful recanalization for acute myocardial infarction (r=-0.49, P=0.01).
Why the study?
Does acute-phase glucose fluctuation correlate with myocardial salvage in patients with acute myocardial infarction?
Population
36 consecutive patients with acute myocardial infarction who underwent successful percutaneous coronary…
Design
Cohort, CMR data analysis performed by consensus of 2 blinded observers
Follow-up
7 days
Authors
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Acute glucose fluctuations may impair salvage post-AMI; leaves open whether stabilization improves outcomes in trials.
Observational (n=36)
No
Does acute-phase glucose fluctuation correlate with myocardial salvage in patients with acute myocardial infarction?
Effect estimate: r = -0.49
p-value: p=0.01
Acute-phase glucose fluctuation is independently associated with impaired myocardial salvage after acute myocardial infarction, suggesting glycemic variability as a potential therapeutic target.
Teraguchi et al. (2013) conducted an observational in Acute Myocardial Infarction (n=36). Acute-phase glucose fluctuation (MAGE) vs. Low glucose fluctuation was evaluated on Myocardial salvage index (MSI) at 7 days (r = -0.49, p=0.01). Acute-phase glucose fluctuation was significantly negatively correlated with the myocardial salvage index 7 days after successful recanalization for acute myocardial infarction (r=-0.49, P=0.01).
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