Key result
Holland/Arkansas vaccination provided marginally better protection against CA99 challenge than Massachusetts/Arkansas vaccination in chickens, though differences were not statistically significant.
Why the study?
Does the Holland/Arkansas vaccination protocol improve protection against CA99 infectious bronchitis virus challenge compared to the Massachusetts/Arkansas protocol in chickens?
Population
Chickens given Massachusetts/Connecticut strains of infectious bronchitis virus vaccines at age 1 day
Comparison
Holland/Arkansas vaccination protocol at 18 days… vs Massachusetts/Arkansas vaccination protocol at…
Design
Preclinical
Follow-up
Challenge at 31 days of age
Authors
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Comparable protection in this avian model leaves open optimal IBV vaccine strain selection; larger trials needed before guiding practice.
Does the Holland/Arkansas vaccination protocol improve protection against CA99 infectious bronchitis virus challenge compared to the Massachusetts/Arkansas protocol in chickens?
p-value: p=not statistically significant
The Holland/Arkansas and Massachusetts/Arkansas vaccination protocols provided similar, non-statistically different protection against CA99 infectious bronchitis virus challenge in chickens.
Martin et al. (2007) studied Infectious bronchitis virus CA99 serotype. Holland/Arkansas vaccination protocol vs. Massachusetts/Arkansas vaccination protocol was evaluated on Protection against CA99 challenge (gross pathology, histopathology, and virus isolation) (p=not statistically significant). Holland/Arkansas vaccination provided marginally better protection against CA99 challenge than Massachusetts/Arkansas vaccination in chickens, though differences were not statistically significant.
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