Subacute Bacterial Endocarditis Complicated by Agranulocytosis; Report of Case With Recovery

Case Reports1 June 1945SUBACUTE BACTERIAL ENDOCARDITIS COMPLICATED BY AGRANULOCYTOSIS; REPORT OF CASE WITH RECOVERYHENRY I. RUSSEK, M.D., RICHARD H. SMITH, M.D., BURTON L. ZOHMAN, M.D., F.A.C.P.HENRY I. RUSSEK, M.D.Search for more papers by this author, RICHARD H. SMITH, M.D.Search for more papers by this author, BURTON L. ZOHMAN, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-22-6-867 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe superiority of penicillin over all other agents thus far employed in the treatment of subacute bacterial endocarditis appears to be established.1, 2, 3, 4, 5, 6 That penicillin may similarly prove to be an important advance in the therapy of agranulocytosis has been hypothesized on the basis of the low toxicity of the drug combined with its high antibacterial potency.7 Supporting this view is the record of three successfully treated cases already reported in the literature.8, 9The occurrence of agranulocytosis in a case ofStreptococcus viridansendocarditis provided an opportunity for testing the effectiveness of penicillin in both...Bibliography1. LOEWEROSENBLATTGREENERUSSELL LPHJM: Combined penicillin and heparin therapy of subacute bacterial endocarditis, Jr. Am. Med. Assoc., 1944, cxxiv, 144-149. CrossrefGoogle Scholar2. LOEWEROSENBLATTGREENERUSSELL LPHJM: Combined penicillin and heparin therapy of subacute bacterial endocarditis, Exhibit, Regional meeting of the Am. Coll. of Phys., New York Acad. Med., Oct. 1944. CrossrefGoogle Scholar3. DAWSONHOBBY MHGL: The clinical use of penicillin, Jr. Am. Med. Assoc., 1944, cxxiv, 611-622. CrossrefGoogle Scholar4. COLLINS BC: Subacute bacterial endocarditis treated with penicillin, Jr. Am. Med. Assoc., 1944, cxxvi, 233. CrossrefGoogle Scholar5. BAEHR G: Penicillin treatment of subacute bacterial endocarditis due to enterococcus, Regional Meet. of Am. Coll. of Phys., New York Hospital, Oct. 20, 1944. Google Scholar6. RUSSEKSMITHDERMAN HIRH: Penicillin in the treatment of subacute bacterial endocarditis, Ann. Int. Med., 1945, xxii, 863-867. Google Scholar7. BETHELLSTURGISMALLERYRUNDLES FHCCOTRW: Blood, a review of the recent literature, Arch. Int. Med., 1944, lxxiv, 131-152. CrossrefGoogle Scholar8. KEEFER CS: Penicillin in the treatment of infections, Jr. Am. Med. Assoc., 1943, cxxii, 1217-1224. CrossrefGoogle Scholar9. SMITHCOHENNICHOLS LBFRG: Agranulocytosis treated with penicillin, Jr. Am. Med. Assoc., 1944, cxxvi, 1027. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication January 5, 1945.Presented at meeting of Richmond County Medical Society, Nov. 8, 1944.From the Cardiovascular Service, U. S. Marine Hospital, Staten Island, N. Y.Published with permission of the Surgeon General, United States Public Health Service. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byENDOCARDITIS COMPLICATED BY AGRANULOCYTOSIS 1 June 1945Volume 22, Issue 6Page: 867-870KeywordsAntibacterial therapyClinical laboratoriesDrug therapyEndocarditisMedical servicesPenicillinResearch laboratoriesStreptococcusSurgeonsToxicity ePublished: 1 December 2008 Issue Published: 1 June 1945 PDF downloadLoading ...