Why the study?
Does penicillin improve recovery in a patient with acute bacterial endocarditis?
Does penicillin improve recovery in a patient with acute bacterial endocarditis?
This historical case report documents the successful treatment and recovery of a patient with acute bacterial endocarditis using penicillin.
Answers are grounded in this paper and cite their sources.
Single case of recovery with penicillin in endocarditis; leaves open generalizability and requires controlled trials.
Case Reports1 March 1946ACUTE BACTERIAL ENDOCARDITIS; A CASE REPORT WITH RECOVERY AFTER TREATMENT WITH PENICILLINROBERT J. CATALDO, M. D.ROBERT J. CATALDO, M. D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-24-3-479 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe term endocarditis may be defined as an inflammation of the lining membrane of the heart, often peculiarly limited to the valves of the heart, when the term valvulitis may appropriately be applied. In some instances the lesion is relatively slight with limitation to a single valvular cusp, to a small area of the mural endocardium, to a papillary muscle, or the lesion may be only a part of an extensive involvement of the heart, a pancarditis, in which the predominating symptoms and signs may be endocardial, myocardial or pericardial.1For clinical purposes, however, the term endocarditis should be divided...Bibliography1. TICE F: The practice of medicine, Vol. VI, 1943, W. F. Prior Co., Hagerstown, Md., pp. 253-273. Google Scholar2. LEVINE SA: Clinical heart disease, 2nd Edition, 1940, W. B. Saunders Co., Philadelphia. CrossrefGoogle Scholar3. FISHBERG AM: Hypertension and nephritis, 4th Edition, 1937, Lea and Febiger, Philadelphia, pp. 547. Google Scholar4. FUTCHERSCOTT PHVC: Four cases of gonococcal endocarditis treated with sulfonamides, with recovery of one, Bull. Johns Hopkins Hosp., 1939, lxv, 377. Google Scholar5. ORGAINPOSTON ESMA: Gonococcal endocarditis, with recovery after sulfapyridine: Report of a case, New England Jr. Med., 1939, ccxxi, 167. CrossrefGoogle Scholar6. GALBREATHHALL WRE: Sulfonamide therapy of bacterial endocarditis; results in forty-two cases, Ann. Int. Med., 1943, xviii, 201. Google Scholar7. GUERRAPEREZ CAVAL F: Chemotherapy against micro-organisms, penicillin in the treatment of endocarditis, Arch. latino-am. de cardiol. y hemat., 1943, xlii, 25. Google Scholar8. DAWSONHOBBY MHGL: The clinical use of penicillin: observations in 100 cases, Jr. Am. Med. Assoc., 1944, cxxiv, 611. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: *Received for publication March 8, 1945.From the First and Third Medical Services (Tufts), Boston City Hospital, and the Department of Medicine, Tufts College Medical School. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byInfective endocarditis in patients with kidney failure: Chronic dialysis and kidney transplantDie septischen Erkrankungen 1 March 1946Volume 24, Issue 3Page: 479-484KeywordsEndocarditisHeartHospital medicineInflammationLesionsMedical servicesMyocardiumPapillary musclesPenicillinSigns and symptoms ePublished: 1 December 2008 Issue Published: 1 March 1946 PDF downloadLoading ...
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