February 1, 1992AJP Heart and Circulatory Physiology

Ventricular fibrillation is not an anodally induced phenomenon in open-chest dogs

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Population

Six open-chest dogs

Comparison

Premature electrical stimulation via bipolar… vs Reversed S2 polarity

Design

Preclinical

Authors

PCP. S. ChenNational Cheng Kung University Hospital

Discussion

Member takes

Implication

Challenges anodal-only VF model in animals; hypothesis-generating for local electrophysiology in arrhythmia mechanisms.

Structured PICO

Population

Six open-chest dogs

Intervention

Premature electrical stimulation (S2) via bipolar electrodes (anodal and cathodal) on the right ventricle

Comparator

Reversed S2 polarity

Outcome

Origin of excitation at the onset of multiple responses or ventricular fibrillationsurrogate

Ventricular fibrillation initiation is determined by the preexisting electrophysiological state at the stimulation site, rather than being strictly an anodally induced phenomenon.

Cite This Study

P. S. Chen (1992) studied this question.

synapsesocial.com/papers/6a918d23a97dfa43b746513d https://doi.org/10.1152/ajpheart.1992.262.2.h365

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Ventricular fibrillation is not an anodally induced phenomenon in open-chest dogs

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Ventricular fibrillation is not an anodally induced phenomenon in open-chest dogs

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider