Key result
Type 1 diabetes in asymptomatic children was associated with increased left ventricular mass index and decreased global longitudinal systolic strain compared to healthy controls.
Why the study?
Does Type 1 diabetes lead to subclinical echocardiographic signs of cardiac dysfunction in asymptomatic children?
Population
60 children, comprising 30 consecutive asymptomatic children with Type 1 diabetes and 30 age- and…
Comparison
Type 1 diabetes (observational exposure) vs Healthy age- and sex-matched controls
Design
Case-control
Authors
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May support early LV monitoring in pediatric T1D; hypothesis-generating for diabetic cardiomyopathy progression.
Case-Control (n=60)
Does Type 1 diabetes lead to subclinical echocardiographic signs of cardiac dysfunction in asymptomatic children?
Children with Type 1 diabetes exhibit subclinical alterations in left ventricular size and longitudinal myocardial deformation, suggesting early signs of diabetic cardiomyopathy.
Hodžić et al. (2016) conducted a case-control in Type 1 diabetes (n=60). Type 1 diabetes vs. Healthy control subjects was evaluated on Echocardiographic signs of subclinical cardiac dysfunction assessed by tissue Doppler strain. Type 1 diabetes in asymptomatic children was associated with increased left ventricular mass index and decreased global longitudinal systolic strain compared to healthy controls.
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