Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
July 1, 2004Perfusion

Mini extracorporeal circuit for coronary artery bypass grafting: initial clinical and biochemical results

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does mini-extracorporeal circulation reduce oxidative stress and the need for blood transfusion compared to conventional CABG in patients undergoing coronary artery bypass grafting?

Population

184 patients undergoing coronary artery bypass grafting (CABG)

Comparison

Mini-extracorporeal circulation for coronary… vs Conventional CABG and off-pump CABG

Design

Cohort

Follow-up

short-term

Authors

WBWim Jan van BovenCardiac SurgeryWGWim B. GerritsenLeiden UniversityFWFrans G. WaandersSt. Antonius Ziekenhuis

Discussion

Loading...

Member takes

Implication

Supports reduced transfusion needs with mini-extracorporeal circulation in CABG; hypothesis-generating and requires randomized confirmation before practice change.

Structured PICO

Does mini-extracorporeal circulation reduce oxidative stress and the need for blood transfusion compared to conventional CABG in patients undergoing coronary artery bypass grafting?

P
Population
184 patients undergoing coronary artery bypass grafting (CABG)
I
Intervention
Mini-extracorporeal circulation (MECC) for coronary artery bypass grafting (MCABG)
C
Comparator
Conventional CABG (CCABG) and off-pump CABG (OPCAB)
O
Outcome
Clinical outcomes, oxidative stress (MDA, allantoin/urate ratios), alveolar shunting, and need for blood transfusionsurrogate

Mini-extracorporeal circulation during CABG may reduce the need for blood transfusions and decrease oxidative stress and alveolar damage compared to conventional CABG.

Limitations

  • Requires confirmation in a prospective study

Cite This Study

Boven et al. (2004) studied this question.

synapsesocial.com/papers/6a919deaa9bc95de3ab605efhttps://doi.org/10.1191/0267659104pf746oa
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Reduction of the inflammatory response following coronary bypass grafting with total minimal extracorporeal circulation2002 · 324 citations
  2. 2Clara Cell Secretory Protein (CC16): Features as a Peripheral Lung Biomarker2000 · 216 citations
  3. 3A Comparison of On-Pump and Off-Pump Coronary Bypass Surgery in Low-Risk Patients2003 · 405 citations
  4. 4Off-pump versus on-pump coronary artery bypass grafting: oxidative stress and renal function2001 · 89 citations