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March 1, 1979CirculationOpen Access

Negative contrast echocardiography: a new method for detecting left-to-right shunts.

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Why the study?

Does negative contrast echocardiography help detect left-to-right shunts in patients with atrial septal defects?

Population

25 patients (13 with intact interatrial septa and 12 with atrial septal defects)

Comparison

Peripheral injection of echocardiographic… vs Patients with intact interatrial septa

Design

Cross-sectional

Authors

AWArthur E. WeymanCardiac ImagingLWL. Samüel WannCardiac ImagingRCRebecca L. CaldwellChevron (Netherlands)

Discussion

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Implication

Negative contrast echocardiography may aid ASD detection; leaves open prospective validation before clinical adoption.

Structured PICO

Does negative contrast echocardiography help detect left-to-right shunts in patients with atrial septal defects?

P
Population
25 patients (13 with intact interatrial septa and 12 with atrial septal defects)
I
Intervention
Peripheral injection of echocardiographic contrast material evaluated using cross-sectional echocardiography (negative contrast echocardiography)
C
Comparator
Patients with intact interatrial septa
O
Outcome
Detection of atrial septal defects (left-to-right shunts) by visualizing contrast flow patterns (negative contrast)surrogate

Negative contrast echocardiography using peripheral contrast injection can help detect atrial septal defects with predominant left-to-right shunting by visualizing an echo-free area in the right atrium.

Cite This Study

Weyman et al. (1979) studied this question.

synapsesocial.com/papers/6a919f47fa99a5b2d5beab0ehttps://doi.org/10.1161/01.cir.59.3.498

Topics

Echocardiography
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Left Ventricular Wall Thickness Measured by Ultrasound1968 · 142 citations
  2. 2Use of Ultrasound to Measure Left Ventricular Stroke Volume1967 · 120 citations
  3. 3Cross-sectional echocardiographic examination of the interatrial septum.1977 · 72 citations
  4. 4Ultrasound Evaluation of Systolic Anterior Septal Motion in Patients With and Without Right Ventricular Volume Overload1974 · 98 citations
  5. 5Mechanism of abnormal septal motion in patients with right ventricular volume overload: a cross-sectional echocardiographic study.1976 · 264 citations