Why the study?
Do prostaglandin E2 levels in cerebrospinal fluid correlate with the severity and clinical outcome in patients suffering from stroke?
Do prostaglandin E2 levels in cerebrospinal fluid correlate with the severity and clinical outcome in patients suffering from stroke?
Prostaglandin E2 levels in the cerebrospinal fluid of stroke patients correlate positively with disease severity and clinical outcome.
May indicate stroke severity; hypothesis-generating case report that should not yet change practice.
In 16 patients suffering from cerebrovascular events, prostaglandin (PG) E2 was measured in their cerebrospinal fluid and correlated with their clinical status and evolution. Prostaglandin E2 ranged from 200-3000 pg (picogram)/ml of cerebrospinal fluid. A positive correlation was found between PG E2 levels and the severity and clinical outcome of the stroke.
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Carasso et al. (1977) studied this question.
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