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The pathogenesis of chronic rhinosinusitis remains poorly understood. The mucosal changes associated with this inflammatory disease have been well studied and described but the underlying bony involvement remains poorly defined. Osteitis and osteomyelitis are terms describing the clinical, pathologic, and radiographic appearance of bone involvement, but no consensus exists regarding the most appropriate terminology. It is still unclear whether bone around the sinuses acts as an innocent bystander becoming secondarily involved in the inflammatory process or whether bone plays a more active role in propagating inflammation.
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Koçak et al. (2002) studied this question.
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