What question did this study set out to answer?

To characterize the clinical and pathologic features and assess management strategies for patients diagnosed with primary small cell carcinoma of the urinary bladder.

February 7, 2005CancerOpen Access

Small cell carcinoma of the urinary bladder

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Authors

NCNicholas W. ChoongMayo Clinic JQJ. Fernando QuevedoMayo Clinic in Arizona JKJudith S. KaurMayo Clinic in Florida

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Implication

Retrospective study shows stage-dependent survival outcomes in bladder small cell carcinoma, suggesting radical cystectomy cures localized disease while advanced stages require chemotherapy.

Key Points

To characterize the clinical and pathologic features and assess management strategies for patients diagnosed with primary small cell carcinoma of the urinary bladder.
Retrospective cohort study of N=44 patients with primary bladder small cell carcinoma diagnosed between 1975 and 2003 at Mayo Clinic (Rochester, MN).
Analyzed clinical presentation, pathologic staging, treatment modalities (radical cystectomy and systemic chemotherapy), and survival over a mean follow-up of 3.2 years.
Overall median survival was 1.7 years, with 5-year survival rates of 63.6% for Stage II, 15.4% for Stage III, and 10.5% for Stage IV disease.
Radical cystectomy achieved a cure in 6 of 8 patients with Stage II bladder small cell carcinoma.
In Stage IV disease, only 2 of 19 patients who received adjuvant chemotherapy were alive at 5 years.

Cite This Study

Choong et al. (2005) studied this question.

synapsesocial.com/papers/6a9224ea43dadb0f154358fa https://doi.org/10.1002/cncr.20903

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Implication

Retrospective study shows stage-dependent survival outcomes in bladder small cell carcinoma, suggesting radical cystectomy cures localized disease while advanced stages require chemotherapy.

Small cell carcinoma of the urinary bladder

Discussion

Member takes

Implication

Key Points

Cite This Study

Small cell carcinoma of the urinary bladder

Discussion

Member takes

Implication

Key Points

Cite This Study

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