Why the study?
Does 19F NMR spectroscopy of sequestered perfluorocarbon emulsion provide an accurate noninvasive assessment of myocardial oxygen tension in rat hearts?
Population
Rats predosed with Oxypherol-ET, with hearts excised and perfused using the Langendorff retrograde technique
Design
Preclinical
Authors
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May enable noninvasive pO2 monitoring in rodent ischemia models; leaves open translation to clinical settings.
Does 19F NMR spectroscopy of sequestered perfluorocarbon emulsion provide an accurate noninvasive assessment of myocardial oxygen tension in rat hearts?
19F NMR spectroscopy of sequestered perfluorocarbon emulsion provides a rapid, noninvasive global measurement of myocardial oxygen tension changes during ischemia and reperfusion in a rat model.
Mason et al. (1992) studied this question.
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