The use of radioactive isotopes in immunological investigations. 9. The reactions of antisera to antigens containing multiple determinant groups

Although it is generally aceepted that the specific combining centres of antibody molecules are in some way complementary to certain polar group- ings in the antigen molecule which determine its serological specificity, very little is known as to the * Present address: Department ofBiochemistry, Glasgow University Veterinary School.*10v (4.38) *SOv (3.75) *ISOv (2.81)Total antibody *1G1 (6.25) *SGI (3-75) *ISGl (5-31) Total antibody *ISOv (11-56) *IGI (1.25) *SGI (1-88) *ISTa (2a19) Total antibody