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Highlights the need for research identifying specific clinical applications to support the use of biomarkers as prognostic indicators in heart failure.
Despite extensive research and numerous publications biomarkers have yet to fulfill their promise as prognostic indicators that can be widely used in the care of patients with heart failure. Specific clinical applications need to be identified for informative analyses of data that emphasize the most directly applicable measures of predictive performance.
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Rector et al. (2010) studied this question.
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