What is the clinical evidence from this study?

Study design: Case Report. Population: Myocardial infarction with non-obstructive coronary arteries (MINOCA) (n=1). Intervention: Cardiac magnetic resonance (CMR). Primary outcome: Diagnosis of etiology of MINOCA.

What does this research mean for the field?

Early cardiac magnetic resonance imaging is effective in identifying the underlying etiology, such as myocarditis, in patients presenting with myocardial infarction with non-obstructive coronary arteries (MINOCA). Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

August 29, 2026European Heart Journal

Early cardiac magnetic resonance leads to diagnose the etiology of myocardial infarction with non-obstructive coronary arteries

Q: What are the key findings of this study?

Early cardiac magnetic resonance identified severe cardiac injury and edema suggestive of myocarditis in a 56-year-old man presenting with MINOCA despite mild symptoms.

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Key result

Early CMR detects severe cardiac injury suggestive of myocarditis in MINOCA despite mild symptoms.

Key Points

To determine the underlying etiology of myocardial infarction with non-obstructive coronary arteries (MINOCA) in a symptomatic patient.
Evaluated a 56-year-old male presenting with chest discomfort, elevated cardiac troponin I, and normal coronary arteries on angiography (N=1).
Performed early cardiac magnetic resonance (CMR) imaging with native T1 and T2 mapping and late gadolinium enhancement, followed by endomyocardial biopsy.
Initial laboratory evaluation demonstrated markedly elevated cardiac troponin I (5911.5 ng/L, reference <26.2 ng/L) and mild eosinophilia (609/µL, 7.1% of leukocytes).
Cardiac magnetic resonance native T1/T2 mapping and late gadolinium enhancement demonstrated pronounced myocardial injury and edema consistent with myocarditis despite mild clinical symptoms.

Study Design

Type

Case Report (n=1)

Structured PICO

Population

A 56-year-old man presenting with chest discomfort and diagnosed with MINOCA, subsequently investigated with cardiac magnetic resonance.

Exposure

Cardiac magnetic resonance (CMR) and endomyocardial biopsy

Outcome

Diagnosis of the etiology of MINOCA

Early cardiac magnetic resonance is valuable for diagnosing the underlying etiology of MINOCA, such as myocarditis, even when clinical symptoms are mild.

Discussion

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Implication

May prompt eosinophilic myocarditis evaluation in unexplained LV dysfunction with eosinophilia; leaves open optimal diagnostic and therapeutic strategies.

Cite This Study

Tsuda et al. (2021) conducted a case report in Myocardial infarction with non-obstructive coronary arteries (MINOCA) (n=1). Cardiac magnetic resonance (CMR) was evaluated on Diagnosis of etiology of MINOCA. Early cardiac magnetic resonance identified severe cardiac injury and edema suggestive of myocarditis in a 56-year-old man presenting with MINOCA despite mild symptoms.

synapsesocial.com/papers/6a924f998bdd4c1dcbe5a291 https://doi.org/10.1093/eurheartj/ehab730

Topics

Coronary CT angiography

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Implication

May prompt eosinophilic myocarditis evaluation in unexplained LV dysfunction with eosinophilia; leaves open optimal diagnostic and therapeutic strategies.

Early cardiac magnetic resonance leads to diagnose the etiology of myocardial infarction with non-obstructive coronary arteries

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Topics

Early cardiac magnetic resonance leads to diagnose the etiology of myocardial infarction with non-obstructive coronary arteries

Key Points

Study Design

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

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