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December 25, 2019Journal of International Medical ResearchOpen Access

The patient's renal function fully recovered (final serum creatinine 1.0 mg/dl, CK 212 U/l) after 13 sessions of haemodialysis despite CK levels reaching at least 300,000 U/l.

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Why the study?

The use of creatine kinase levels to predict long-term renal function in rhabdomyolysis remains controversial.

Does haemodialysis improve renal function in a patient with severe rhabdomyolysis and acute kidney injury?

Population

One 29-year-old man with severe rhabdomyolysis and AKI following ketamine use

Design

Case report

Authors

STShang‐Feng TsaiJTJun-Li TsaiCCCheng‐Hsu Chen

Discussion

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Overview

Full renal recovery occurred despite extreme CK elevation and AKI; leaves open CK's utility for predicting long-term renal outcomes.

Structured PICO

Does haemodialysis improve renal function in a patient with severe rhabdomyolysis and acute kidney injury?

P
Population
1 patient, 29-year-old man with severe rhabdomyolysis and acute kidney injury (AKI) following ketamine use.
I
Intervention
Intravenous normal saline (4000 ml/day) and 13 sessions of haemodialysis
O
Outcome
Renal function recovery (serum creatinine and creatine kinase levels)surrogate

Severe rhabdomyolysis with extremely high CK levels does not necessarily preclude full renal recovery when treated with haemodialysis.

Cite This Study

Tsai et al. (2019) studied this question.

synapsesocial.com/papers/6a9258224913c8e05db883cdhttps://doi.org/10.1177/0300060519888105
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