Why the study?
Do depressive symptoms increase the risk of first or recurrent cardiac events in healthy individuals and coronary patients?
Do depressive symptoms increase the risk of first or recurrent cardiac events in healthy individuals and coronary patients?
Epidemiological evidence links depressive symptoms to an increased risk of incident and recurrent coronary events, though the biological mechanism remains unknown.
During the past decade approximately 20 epidemiological studies demonstrated that the number of depressive symptoms manifested by a subject increased the risk of a first coronary event in apparently healthy individuals and the risk of a recurrent cardiac event in coronary patients. The biological basis of this association is still unknown. It has also to be demonstrated that a reduction in the feelings of depression or distress reduces the risk of a first or recurrent cardiac event.
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Ad Appels (2002) studied this question.
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