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January 1, 2020Patient Preference and AdherenceOpen Access

Compared to adequate health literacy, low health literacy was associated with lower knowledge of drug indications (64.1% vs 83.1%, p<0.001) and understanding of instructions (68.1% vs 82.9%, p=0.001), but higher self-reported adherence (65.6% vs 56.0%, p=0.010).

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Why the study?

The study was conducted to examine associations between health literacy and several medication self-management constructs among adults with uncontrolled hypertension.

Population

919 health center patients with uncontrolled hypertension from the Chicago area

Comparison

Varying levels of health literacy (likely limited vs possibly limited vs likely adequate)

Design

Cross-sectional study

Authors

SPStephen D. PersellKKKunal N. KarmaliJLJi Young Lee

Discussion

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Overview

Health literacy was associated with medication self-management; leaves open whether literacy interventions improve adherence or control in uncontrolled hypertension.

Structured PICO

P
Population
919 adults with uncontrolled hypertension from community health centers in the Chicago area
O
Outcome
Medication self-management constructs (medication reconciliation, knowledge of drug indications, understanding instructions and dosing, and self-reported adherence over 4 days)patient reported

Among patients with uncontrolled hypertension, low health literacy is associated with poorer knowledge and understanding of medications, but paradoxically higher self-reported adherence.

Cite This Study

Persell et al. (2020) studied this question.

synapsesocial.com/papers/6a92657afd03cddea19630achttps://doi.org/10.2147/ppa.s226619
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Health Literacy and Its Role in Promoting Medication Adherence Among Hypertension Patients2026 · 1 citations
  2. 2Association between health literacy and medication adherence in patients with hypertension: a cross-sectional study2025 · 7 citations
  3. 3Association between medication literacy and blood pressure control among hypertensive patients2023 · 11 citations
  4. 4The Association Between Medication Literacy and Blood Pressure Control in Patients With Hypertension in a Multi-ethnic County in China2026
  5. 5Assessment of Medication Adherence and Its Association with Health Literacy Among Hypertensive Patients2024