Population
280 male F344 rats, 6 weeks old, azoxymethane (AOM)-induced intestinal carcinogenesis model
Comparison
Flavoglaucin, shikonin, gingerol, oleanolic… vs AOM alone or basal diet control
Design
Preclinical
Follow-up
one year
Authors
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Does not inform human practice; leaves open chemopreventive potential of flavoglaucin in clinical settings.
Flavoglaucin, shikonin, and gingerol demonstrated chemopreventive effects against azoxymethane-induced intestinal carcinogenesis in a rat model.
Yoshimi et al. (1992) studied this question.
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