January 12, 1969Acta Medica Scandinavica
EFFECT OF APTIN, A β‐ADRENERGIC BLOCKING AGENT, IN ARTERIAL HYPERTENSION
Why the study?
Does Aptin reduce blood pressure in patients with moderate arterial hypertension?
Population
12 patients with moderate arterial hypertension
Comparison
Aptin (beta-adrenergic blocking agent) vs Alternative arm of cross-over design
Design
RCT, double-blind
Authors
Discussion
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Member takes
Implication
Supports Aptin for systolic BP reduction in moderate hypertension; confirms efficacy in this RCT.
Structured PICO
Does Aptin reduce blood pressure in patients with moderate arterial hypertension?
P
Population
12 patients with moderate arterial hypertension
I
Intervention
Aptin (beta-adrenergic blocking agent)
C
Comparator
Alternative arm of cross-over design (not explicitly specified)
O
Outcome
Systolic and diastolic blood pressure at restsurrogate
Aptin provides a moderate reduction in systolic blood pressure in patients with moderate arterial hypertension and is well tolerated.
Cite This Study
Furberg et al. (1969) studied this question.