Why the study?
Does modified ultrafiltration affect plasma fentanyl levels in neonates and infants undergoing congenital heart surgery?
Population
Neonates and infants undergoing repair of congenital heart defects (n=5) and an in vitro experimental model.
Design
Case_series
Authors
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MUF-associated fentanyl rise in this case warrants vigilance; leaves open need for adjusted dosing in pediatric congenital heart surgery.
Does modified ultrafiltration affect plasma fentanyl levels in neonates and infants undergoing congenital heart surgery?
Modified ultrafiltration significantly increases plasma fentanyl levels in pediatric patients undergoing congenital heart surgery, which should be considered for anesthetic management.
Taenzer et al. (2005) studied this question.
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