Why the study?
Does preeclampsia increase the risk of developing subsequent diabetes in women?
Does preeclampsia increase the risk of developing subsequent diabetes in women?
Women with a history of preeclampsia have a significantly higher risk of developing subsequent diabetes, independent of gestational diabetes.
May inform enhanced postpartum diabetes surveillance after preeclampsia; leaves open causality and optimal strategies.
OBJECTIVE: Determine whether preeclampsia is associated with developing diabetes. METHODS: Subsequent diabetes was ascertained using ICD-9 codes, pharmacy and glucose data in a retrospective cohort study of 2,032 women with preeclampsia and 29,431 without preeclampsia. RESULTS: During a median follow-up of 8.2 years, 342 women developed diabetes. Preeclampsia was associated with a higher risk of diabetes adjusting for age, primigravidity, and gestational diabetes (hazard ratio, HR 1.82, 95%CI 1.26, 2.62) and in women without gestational diabetes (n = 30,109; HR 1.86, 95%CI 1.22, 2.84). CONCLUSION: Women with preeclampsia have greater risk of developing diabetes, even in the absence of gestational diabetes.
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Carr et al. (2009) studied this question.
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