Key result
Early-onset preeclampsia, cardiometabolic risk factors, and older age are linked to later CVD or hypertension.
Why the study?
Preeclampsia is associated with future cardiovascular disease, yet systematic approaches to identify women requiring intensified prevention are lacking.
Population
17,434 primiparous women with preeclampsia in Denmark from 2004-2018
Comparison
Women with preeclampsia stratified by risk factors for chronic hypertension or CVD
Design
Nationwide register-based cohort study using Poisson regression models
Follow-up
Up to December 2022
Authors
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May support intensified monitoring in high-risk preeclampsia subgroups; extends risk stratification but remains hypothesis-generating.
Cohort (n=17,434)
Yes
In women with a history of preeclampsia, factors such as early-onset preeclampsia, smoking, diabetes, low education, and higher BMI identify subgroups at particularly high risk for future chronic hypertension and cardiovascular disease.
Nielsen et al. (2026) conducted a cohort in Preeclampsia (n=17,434). Risk factors (early-onset preeclampsia, smoking, diabetes, low education, high BMI, age) vs. Absence of respective risk factors was evaluated on Later chronic hypertension or cardiovascular disease (CVD). Among women with preeclampsia, risk factors for later chronic hypertension or CVD included early-onset preeclampsia, smoking, diabetes, low education, higher age, and BMI ≥ 25 kg/m2.
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