Population
Nemaline myopathy and some cardiac muscles
Design
Preclinical
Authors
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Does not yet inform clinical management of nemaline myopathy; extends ultrastructural models of Z-band organization in animal sarcomeres.
The study elucidates the 3D structure of the nemaline rod Z-band, revealing the arrangement of actin filaments and their probable cross-linking by alpha-actinin.
Morris et al. (1990) studied this question.
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