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August 29, 2026The Egyptian Journal of Neurology Psychiatry and NeurosurgeryOpen Access

Association of the glucose-to-lymphocyte ratio with stroke-associated pneumonia among acute ischaemic stroke patients with dysphagia: a secondary analysis of hospital-based observational data

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Authors

TTTran Huu ThongNHNguyen Thi Thu Hien

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Overview

Observational study finds glucose-to-lymphocyte ratio does not independently predict stroke-associated pneumonia in dysphagic stroke patients, indicating limited utility in routine risk scoring.

Key Points

  • To assess whether admission glucose-to-lymphocyte ratio is independently associated with stroke-associated pneumonia and adds incremental predictive value in acute ischaemic stroke patients with dysphagia.
  • Conducted a secondary analysis of observational data from 681 acute ischaemic stroke patients with dysphagia treated at a tertiary referral hospital in Hanoi, Vietnam.
  • Assessed the glucose-to-lymphocyte ratio (GLR) from admission blood samples per 1-standard-deviation increase and by quartiles, adjusting for clinical covariates with multivariable logistic regression and evaluating discrimination using area under the curve (AUC).
  • Stroke-associated pneumonia occurred in 70 of 681 patients (10.3%; 95% CI 8.2 to 12.8).
  • Each 1-standard-deviation increase in GLR was associated with higher odds of pneumonia in crude analysis (OR 1.24, 95% CI 1.001 to 1.53), but this attenuated after multivariable adjustment (adjusted OR 1.10, 95% CI 0.86 to 1.41).
  • GLR alone exhibited poor discrimination (AUC 0.58), and adding GLR to an established clinical model did not improve discrimination (AUC 0.820 to 0.821; difference 0.001, 95% CI −0.002 to 0.012).

Cite This Study

Thong et al. (2026) studied this question.

synapsesocial.com/papers/6a92997e8e5d7d1fc0c116edhttps://doi.org/10.1186/s41983-026-01225-x
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Association of Admission Glucose‐to‐Lymphocyte Ratio With 90‐Day Functional Outcome in Patients With Acute Ischemic Stroke Treated With Intravenous Thrombolysis2026
  2. 2Association between the Glucose-to-Lymphocyte Ratio and Mortality in Patients with Ischemic Stroke: Based on the MIMIC-IV Database2026
  3. 3Prognostic value of glucose-to-lymphocyte ratio for all-cause mortality and consciousness impairment in critically ill cerebrovascular disease patients2025 · 1 citations
  4. 4Correlation between glucose-to-lymphocyte ratio and all-cause mortality in patients with pneumonia2026
  5. 5Association between glucose-to-lymphocyte ratio and risk of in-hospital mortality in patients with acute ischemic stroke: a retrospective cohort study based on the MIMIC-IV database2026