Case report reveals diagnostic ambiguity of HHV-6 in an immunocompetent adult with meningitis, highlighting that clinical recovery can avert unnecessary antiviral therapy.
Consider human herpesvirus 6 (HHV‐6) in immunocompetent adults with viral meningitis when standard tests are negative. Qualitative CSF PCR requires cautious interpretation because it cannot exclude chromosomally integrated HHV‐6. Serial CSF improvement and rapid clinical recovery may support probable self‐limited infection and help avoid unnecessary ganciclovir or foscarnet therapy.
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Taha et al. (2026) studied this question.
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