What does this research mean for the field?

Tannic acid exhibits significant, concentration-dependent in vitro anthelmintic activity against Pheretima posthuma, with its efficacy at 60 mg/mL being comparable to the standard drug albendazole. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the in vitro anthelmintic efficacy of tannic acid against Indian earthworms (Pheretima posthuma) compared with the standard anthelmintic drug albendazole.

August 29, 2026Open Access

Evaluation of the Anthelmintic Efficacy of Tannic Acid in an in Vitro Earthworm Model (Pheretima Posthuma)

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Authors

DBDasrao Ashok Patil, Dr. Kavaljit Satish Birajdar, Dr. Prashant Premnath Mane, Dhruti Prashant Mane, Suraj Sudhakar More, Suraj Dilip BhagatRayat Shikshan Sanstha

Discussion

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Implication

In vitro study reveals concentration-dependent anthelmintic activity of tannic acid in earthworms, indicating its therapeutic potential as an antiparasitic agent.

Key Points

To evaluate the in vitro anthelmintic efficacy of tannic acid against Indian earthworms (Pheretima posthuma) compared with the standard anthelmintic drug albendazole.
Adult earthworms (Pheretima posthuma, n = 6 per group) were exposed to tannic acid at 20, 40, and 60 mg/mL, with 20 mg/mL albendazole serving as the reference control.
Anthelmintic activity was quantified by recording mean times to worm paralysis and death, evaluated via one-way ANOVA followed by Dunnett's multiple comparison test.
Tannic acid caused concentration-dependent paralysis at 6.200 ± 0.1897 min (20 mg/mL), 4.633 ± 0.1506 min (40 mg/mL), and 3.000 ± 0.1414 min (60 mg/mL).
Mean time to death for tannic acid was 12.117 ± 0.1169 min at 20 mg/mL, 7.183 ± 0.1602 min at 40 mg/mL, and 5.667 ± 0.0817 min at 60 mg/mL, compared to 6.450 ± 0.1049 min (paralysis: 3.367 ± 0.1862 min) for 20 mg/mL albendazole.

Cite This Study

Dasrao Ashok Patil, Dr. Kavaljit Satish Birajdar, Dr. Prashant Premnath Mane, Dhruti Prashant Mane, Suraj Sudhakar More, Suraj Dilip Bhagat (2026) studied this question.

synapsesocial.com/papers/6a9299c88e5d7d1fc0c11f9d https://doi.org/10.5281/zenodo.22122890

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August 29, 2026Open Access

Evaluation of the Anthelmintic Efficacy of Tannic Acid in an in Vitro Earthworm Model (Pheretima Posthuma)

View Full Paper

Ask AI

Bookmark

Authors

DBDasrao Ashok Patil, Dr. Kavaljit Satish Birajdar, Dr. Prashant Premnath Mane, Dhruti Prashant Mane, Suraj Sudhakar More, Suraj Dilip BhagatRayat Shikshan Sanstha

Discussion

Member takes

Implication

In vitro study reveals concentration-dependent anthelmintic activity of tannic acid in earthworms, indicating its therapeutic potential as an antiparasitic agent.

Key Points

To evaluate the in vitro anthelmintic efficacy of tannic acid against Indian earthworms (Pheretima posthuma) compared with the standard anthelmintic drug albendazole.
Adult earthworms (Pheretima posthuma, n = 6 per group) were exposed to tannic acid at 20, 40, and 60 mg/mL, with 20 mg/mL albendazole serving as the reference control.
Anthelmintic activity was quantified by recording mean times to worm paralysis and death, evaluated via one-way ANOVA followed by Dunnett's multiple comparison test.
Tannic acid caused concentration-dependent paralysis at 6.200 ± 0.1897 min (20 mg/mL), 4.633 ± 0.1506 min (40 mg/mL), and 3.000 ± 0.1414 min (60 mg/mL).
Mean time to death for tannic acid was 12.117 ± 0.1169 min at 20 mg/mL, 7.183 ± 0.1602 min at 40 mg/mL, and 5.667 ± 0.0817 min at 60 mg/mL, compared to 6.450 ± 0.1049 min (paralysis: 3.367 ± 0.1862 min) for 20 mg/mL albendazole.

Cite This Study

Dasrao Ashok Patil, Dr. Kavaljit Satish Birajdar, Dr. Prashant Premnath Mane, Dhruti Prashant Mane, Suraj Sudhakar More, Suraj Dilip Bhagat (2026) studied this question.

synapsesocial.com/papers/6a9299c88e5d7d1fc0c11f9d https://doi.org/10.5281/zenodo.22122890

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