Why the study?
Does human neuropeptide Y potentiate alpha1-adrenergic blood pressure responses in healthy volunteers?
Population
12 healthy volunteers
Comparison
Intravenous infusion of phenylephrine with… vs Intravenous infusion of phenylephrine without hNPY
Design
Other, single-blind
Authors
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High-dose NPY effects in healthy volunteers should not change practice; hypothesis-generating for disease states.
Does human neuropeptide Y potentiate alpha1-adrenergic blood pressure responses in healthy volunteers?
High-dose human neuropeptide Y potentiates alpha1-adrenergic vasoconstriction in the systemic arterial circulation of healthy volunteers.
Schuerch et al. (1998) studied this question.
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