May 1, 2003Arteriosclerosis Thrombosis and Vascular Biology

Expression of Human Scavenger Receptor B1 on and in Human Platelets

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Why the study?

Is the expression of hSR-B1/CLA-1 on platelets altered in patients with atherosclerotic disease compared to controls?

Population

Patients with atherosclerotic disease and control subjects (human platelets and megakaryocytes)

Design

Case-control

Authors

HIHitomi ImachiKagawa University KMKoji MuraoKagawa University WCWen-Ming CaoKagawa University

Discussion

Member takes

Implication

Reduced platelet hSR-B1/CLA-1 associates with atherosclerosis and aggregation; leaves open biomarker or target utility pending validation.

Structured PICO

Is the expression of hSR-B1/CLA-1 on platelets altered in patients with atherosclerotic disease compared to controls?

Population

Patients with atherosclerotic disease and control subjects (human platelets and megakaryocytes)

Comparator

Control subjects

Outcome

Expression levels of hSR-B1/CLA-1 on plateletssurrogate

Reduced expression of the HDL receptor hSR-B1/CLA-1 on platelets is associated with atherosclerotic disease and increased platelet aggregation, suggesting its potential as a clinical marker.

Cite This Study

Imachi et al. (2003) studied this question.

synapsesocial.com/papers/6a929d59eb36ee4226182ba5 https://doi.org/10.1161/01.atv.0000067429.46333.7b

View Full Paper

Ask AI

Bookmark

Implication

Reduced platelet hSR-B1/CLA-1 associates with atherosclerosis and aggregation; leaves open biomarker or target utility pending validation.

Expression of Human Scavenger Receptor B1 on and in Human Platelets

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Expression of Human Scavenger Receptor B1 on and in Human Platelets

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider