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Demonstrates enhanced vascular imaging using multi-VENC phase contrast MRA in peripheral arterial occlusive disease, suggesting a viable non-contrast alternative.
Phase contrast MR angiography (PC-MRA) depends on phase shifts caused by blood flow. Generally, PC sequences employ one VENC (velocity-encoding) value for each encoded spatial direction to optimize the signal in major vessels during peak systolic flow. We compared a mono-(30) with a multi-(20/30/45) VENC-PC-MRA technique in 10 patients with peripheral arterial occlusive disease. In all patients, the multi-VENC-PC sequence enhanced the vascular signal in vessels with very different flow velocities in one measurement. Large fields-of-view can be measured in a relatively short examination time to obtain an overview of the peripheral arterial system of the patient when contrast-enhanced MRA is not possible.
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Goyen et al. (2000) studied this question.
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